Laparoscopy and Well-Differentiated Papillary Mesothelioma of the Peritoneum

Mesothelioma, is a rare and poorly understood disease that arises from mesothelial cells lining serous cavities. From a histopathologic point of view there are epithelial, connective tissue and mixed varieties. Although commonly found in the pleura, the peritoneum is involved in 20-40% of cases.1-5 Well-Differentiated Papillary Mesothelioma of the Peritoneum (WDPMP) is a type of epithelial mesothelioma which typically shows benign biological behavior,6-12 although several cases with a more aggressive form have been reported.13-18 Being uncommon, it lacks of specific clinical and radiological manifestations,19-21 and it is difficult to obtain precise information regarding its natural history and optimal management. The diagnosis is challenging and the delay is a component of the clinical picture of these patients. This chapter evaluates the applicability of laparoscopy when this entity is suspected.